Pediatric Pain &
The UCLA Pediatric Pain & Palliative Care Program is dedicated to alleviating pain and other causes of distress for children with serious, chronic or life-threatening illnesses, with a focus on:
• Providing support to children and families
• Relieving pain and other symptoms
• Facilitating communication among family members and healthcare providers
• Enhancing the child’s quality of life
Unlike hospice, palliative care can include curative treatments in early stages of illness and is not just focused on children with diseases for which a cure is unlikely. Its focus is on quality of life for all suffering or sick children.
Our pain and palliative care team is dedicated to alleviating pain and other symptoms that children with complex illnesses may experience. Our goal is to provide the best quality of life possible for our pediatric patients and their families.
Our team provides recommendations for many different types of treatments — both medical and non-medical — to help with pain, nausea, anxiety and other discomforts associated with illness. We are an interdisciplinary team that includes physicians; a nurse practitioner; a social worker who heads a special bereavement program for families of children who have passed away; and a research psychologist who helps identify, develop, and study new types of services for the children we serve, including home care and telemedicine.
We also provide connections with the chaplain, child life program (which helps patients cope with their illness and hospitalization) and Heart Touch, a program that offers massage therapy for our patients. In addition, our nurse practitioner is trained to provide mind-body support for our patients, including aroma therapy, massage, yoga and Reiki energy therapy.
Studies show that patients who receive the type of palliative care we offer not only may live longer but enjoy happier lives. They often report less suffering, reduced pain, enhanced feelings of well-being, lower rates of depression and may experience fewer days in the hospital.
Family members may also benefit from the extra emotional and spiritual support they receive from our palliative care professionals.
The Mattel Children's Hospital UCLA Comfort Corner is a space for pediatric patients, families and healthcare providers to relax and escape the hectic hospital environment. We provide a serene setting with tea, hot chocolate, aromatherapy and a listening ear.
For parents, we provide resources on how you can actively help your child cope with his/her symptoms. For healthcare providers, we offer clinical consultation and informal debriefing opportunities, as well as team meetings for groups of clinicians involved in a child’s care.
Our interdisciplinary team of pain and palliative care physicians and other clinicians provide outpatient services for symptom management that take into account the child’s and family's needs. The program has a special focus on pain and symptoms associated with complex medical conditions or chronic pain problems.
We also provide mind-body care that integrates all different aspects of a patient's needs: psychological, physical and social. Integrated into our outpatient program, we work together with music and art therapists, massage and craniosacral therapists, hypnotherapy and biofeedback clinicians, yoga and mindfulness instructors and physical therapists, psychologists and child psychiatrists.
If you think your child could benefit from pediatric pain and palliative care services, please ask his/her doctor for a referral.
Healthcare providers recognize the benefits of pain management and palliative care services for their patients and typically welcome our specialists to the healthcare team.
PI: Laura A. Payne, PhD
The primary goal of this research project is to characterize mechanisms underling primary dysmenorrhea (PD; menstrual pain without an identified organic cause) in older adolescent girls and young adult women (ages 16-25). This innovative study uses recently developed techniques to better understand how and why adolescents and women with PD experience pain. In addition, this study is the first of its kind to explore pain responses in PD in younger populations. We hope this study can help identify girls at risk for the development of future chronic pain problems and potentially inform new interventions and prevention strategies. We are recruiting girls ages 16-25 both with and without menstrual pain. Study participation involves attending one intake session at our research offices at UCLA, and then 3 separate laboratory sessions during each of 3 phases of the menstrual cycle. Laboratory sessions will involve a undergoing a series of heat and cold tasks, as well as collecting saliva samples. The intake visit lasts about 1 hour; each laboratory session lasts about 1 ½ hours. Participants are paid $25 for the intake session, $50 for the first laboratory visit, $75 for the second laboratory visit, and $100 for the final laboratory visit. For more information, please contact Laura Seidman at (310) 825-6907.
PI: Laura A. Payne, PhD
Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) is a very common problem, with 20-25% of girls and women experiencing severe symptoms that interfere with functioning. Yet, no non-drug treatments for PD have been rigorously evaluated. The current study aims to test the feasibility and preliminary efficacy of a brief group therapy focused on reducing pain catastrophizing in adolescents and young adults (ages 16-21) with menstrual pain. Study participants will undergo a laboratory session involving testing responses to heat and cold pain both before and after treatment. Treatment involves 5 sessions held over a 6-week period. Participants are paid $25 for the first laboratory session, $75 for the laboratory session after treatment, and $10 for each of 3 monthly questionnaire assessments following the completion of the second laboratory session. For more information, please contact Laura Seidman at (310) 825-6907.
PI: Jennie C. I. Tsao, PhD
Headache pain is a common and significant problem for adolescents that can negatively impact quality of life. The aim of the current study is to develop and test a mobile application (app) ThinkMe, to assist teens with self-management of recurring headaches. Teens aged 13-17 years with recurring headaches not due to organic causes and with an Iphone are invited to participate in a user testing trial of the ThinkMe app. Eligible teens will be randomly assigned to receive either the ThinkMe intervention or to a care as usual control group. Teens assigned to the ThinkMe app will complete questionnaires online and use the ThinkMe app each day for 30 days to track their headaches and to receive daily suggestions for how to cope with their headache pain. At the end of the trial, teens will complete another set of questionnaires, and will complete follow-up questionnaires at 3- and 6-month follow-ups. Teen assigned to the control group will also complete the same questionnaires at the same time points and will continue with their usual care. Parents of all teens will also complete questionnaires at these same time points. Teens and parents may each earn up to $100 for completing the study questionnaires, for a total of up to $200 per family. Payment per participant will be distributed as follows: $10 for completing baseline questionnaires; $20 for completing the post-intervention questionnaires; $30 for completing 3-month follow-up; $40 for completing 6-month follow-up. This study is being conducted in conjunction with a technology company, Inflexxion, Inc. based in Boston, MA. For more information, please contact Ravi Bhatt at (217) 414-1825.
PI: Jennie C. I. Tsao, PhD
Functional abdominal pain is one of the most frequent sources of chronic pain in adolescents. This study will lay the groundwork for the development of a fully-functioning mobile application (app) to support and motivate teens to adopt and maintain self-management skills for recurrent abdominal pain as well as video-tutorials for parents to reinforce self-care skills at home. Teens aged 13-17 with recurrent abdominal pain not due to organic causes and with an Iphone are invited to participate in a user testing trial of a prototype of the planned app. Eligible teens will complete questionnaires online and then use the app for 30 days. They will be asked to use the app daily to receive messages on how to cope with their abdominal pain. After the 30 day trial, teens will complete another set of questionnaires. Parents of enrolled teens will also complete questionnaires before and after their child uses the app. Adolescents will receive $25 and parents will receive $50 for their participation. This study is being conducted in conjunction with a technology company, Bodimojo, Inc. based in Boston, MA. For more information, please contact Laura Seidman at (310) 825-6907.
PI’s: Jennie C. I. Tsao, PhD & Kirsten Tillisch, MD
Irritable bowel syndrome (IBS) is a disorder of the brain-gut axis characterized by recurrent abdominal pain and altered bowel habits, affecting 10-20% of children. This study sought to examine the pathways linking the gut, the brain and behavior in children with IBS. The project aimed to: 1) Determine the feasibility and acceptability of an fMRI protocol to assess brain structure and resting state networks in children (aged 7-17 years) with IBS and healthy, age- and sex- matched controls (HC); 2) Compare IBS and HC subjects’ structural and functional brain parameters to determine whether they are supportive of the alterations in cortical thickness, white matter properties and resting state brain activity found in adult patients with IBS and to provide data to determine effect size for future power analyses; 3) Assess for structural and resting state functional brain correlates with a behavioral index of endogenous pain inhibition, Conditioned Pain Modulation (CPM), within and across IBS and HC groups. 4) Identify stool microbial composition patterns that may be associated with altered pain inhibition and/or brain parameters within and across IBS and HC groups. Since IBS is more common in girls than boys and to avoid the confounding effects of sex, only girls were enrolled in this pilot study. 11 girls with IBS and 14 control girls completed the CPM protocol which involved standardized administrations of cold and heat pain stimuli. Structural, diffusion tensor and functional MRI scans were completed for these 25 subjects; food diaries were completed by 24 subjects and stool samples were collected from 25 subjects. Thus, the fMRI protocol is feasible and acceptable; all eligible participants completed the scans without adverse events. The data quality from the acquired scans was excellent for a pediatric population where movement is often a concern. Four resting state functional MRI scans (1 IBS, 3 healthy control) and 1 DTI scan (healthy control) failed quality assessment due to excessive motion; all structural scans were of good quality. The processed scans are parcellated into 156 brain regions. Region of interest comparisons will be made between groups for gray matter volumes, white matter fractional anisotropy and mean diffusivity, and correlation analyses performed with pain metrics. Resting state functional connectivity will be compared between groups. Microbiota data will be stored at -80 ºC until analysis can be completed.
PI: Elana E. Evan, PhD
When children confront serious illnesses, reliance on their parents and/or primary caregivers for communication with the healthcare team and other support networks becomes the norm. Differences between children’s and parents’ reports of children’s symptoms have been documented. Parents may need help in learning to understand and reflect their child’s symptoms, while children can learn how to better express their symptoms to their parents so their symptom management needs are met via proxy reporting by their parents. This study tests feasibility of a manualized communication intervention for children with serious illnesses and their parents. The primary goal is to help the child/parent dyad to maximize the parent’s understanding of their child’s symptoms and to enhance the child’s abilities to report their symptoms to their parents. With improved communication, parents would be expected to become more accurate proxy reporters for their children, a critical factor for good symptom management and improved quality of life in pediatric palliative care. Dr. Evan, will recruit, with the discretion of the treating team, families to participate in the intervention. Pediatric patients with serious GI, cardiomyopathy, Cystic fibrosis and oncologic disease between the ages of 10-21 are eligible. The intervention will consist of three sessions, scheduled in the place most comfortable for the participating family members (e.g. home, hospital or outpatient facility). Participants will complete symptom and demographic questionnaires, learn symptom communication strategies. Both pediatric patient and primary caregiver will each receive $10 gift cards at the completion of each of the 3 sessions. This information along with analyzed assessment data will be applied to future changes in the intervention.
The main goal of this study is to investigate the relationship between genes, stress, and pain. The findings of this study will contribute to our understanding of the connection between genes, stress, and pain in adult and child research participants and their parents and may help identify people at risk for developing pain. We are recruiting healthy children and children with chronic pain (ages 8 through 21) and their biological parent(s) to complete one lab session at UCLA or at home which lasts less than 50 minutes. Brothers and sisters may also participate. During the lab session each participant will answer questions about health, personal attitudes, depression, anxiety, and trauma, and a sample of saliva (spit) will be collected. Participants can also complete the questionnaires and provide the sample of saliva (spit) at home and mail the questionnaires and sample back to us. For more information, please contact Loran Hayes for the Genes, Stress, and Pain Study at the UCLA Pediatric Pain Program at (310) 475-3191 ext. 225.
The UCLA Mattel Children’s Hospital is seeking healthy children ages 8 through 17 years old for a study examining how children who are not being treated for pain and children with chronic pain (headaches) as well as their parents respond to stress/pain in a controlled, safe, laboratory setting. The study involves the child and his/her parents attending one session at UCLA. The child and parents will answer questions about their health, including experiences with pain and other bodily symptoms, mood, and views about how different people respond to pain. These questions will take about 1 hour to complete. Participants will also perform four brief lab stress/pain tasks and a sample of saliva (spit) will be taken to analyze for stress hormones. Each visit to UCLA will last about 3 ½ to 5 hours depending on how many family members participate. Each participating family member will receive $50 in cash and free parking. For more information please call the Stress/Pain Responses in Parents and Children Study or Mona Moieni at the UCLA Pediatric Pain Program at (310) 475-3191 ext. 223.
The Pediatric Pain Program at UCLA is conducting a study on Iyengar Yoga for young people aged 16-22 years with Irritable Bowel Syndrome (IBS). The study involves young people completing an 8-week course of yoga. Participants will also be asked to attend two laboratory sessions at UCLA which will involve completing questionnaires, interviews, lab stress tasks, and saliva samples and will last approximately 3 hours. All yoga classes will be free, and we will cover UCLA parking. For more information, please call (310) 475-3191 ext. 221 and leave a message for Laura Cousins/IBS Yoga Study.
The History and Narratives of Pain Study (PI's: Lonnie Zeltzer, MD and Jennie Tsao, PhD) is recruiting children and adolescents ages 8-17 with chronic pain. The study requires that the child/adolescent and a parent (mother or father) complete one set of questionnaires. These are the same questionnaires that are completed for the initial clinic visit (either at Whole Child or UCLA). In order to reduce the burden of time on patients/participants, we ask permission from all new eligible patients who have completed the questionnaires to release these for research so that completing another set is not necessary. If you have any questions, please call Loran Hayes at (310) 475-3191 ext. 225 or email at firstname.lastname@example.org.
View a list of
List of Publications (2010-2016)
Recklitis CJ, Diller LR, Li X, Najita J, Robison LL, Zeltzer L. Suicide ideation in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2010 Feb 1;28(4):655-61.
Goldsby RE, Liu Q, Nathan PC, Bowers DC, Yeaton-Massey A, Raber SH, Hill D, Armstrong GT, Yasui Y, Zeltzer L, Robison LL, Packer RJ. Late-occurring neurologic sequelae in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2010 Jan 10;28(2):324-31.
Buie T, Campbell DB, Fuchs GJ 3rd, Furuta GT, Levy J, Vandewater J, Whitaker AH, Atkins D, Bauman ML, Beaudet AL, Carr EG, Gershon MD, Hyman SL, Jirapinyo P, Jyonouchi H, Kooros K, Kushak R, Levitt P, Levy SE, Lewis JD, Murray KF, Natowicz MR, Sabra A, Wershil BK, Weston SC, Zeltzer L, Winter H. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics. 2010 Jan;125 Suppl 1:S1-18.
Kahalley LS, Robinson LA, Tyc VL, Hudson MM, Leisenring W, Stratton K, Zeltzer L, Mertens AC, Robison LL, Hinds PS. Attentional and executive dysfunction as predictors of smoking within the Childhood Cancer Survivor Study cohort. Nicotine Tob Res. 2010 Apr;12(4):344-54.
Yazdani S, Evan E, Roubinov D, Chung PJ, Zeltzer L. A longitudinal method of teaching pediatric palliative care to interns: preliminary findings regarding changes in interns' comfort level. Palliat Support Care. 2010 Mar;8(1):35-40.
Schultz KA, Chen L, Chen Z, Zeltzer LK, Nicholson HS, Neglia JP. Health and risk behaviors in survivors of childhood acute myeloid leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 Jul 15;55(1):157-64.
Stuber ML, Meeske KA, Krull KR, Leisenring W, Stratton K, Kazak AE, Huber M, Zebrack B, Uijtdehaage SH, Mertens AC, Robison LL, Zeltzer LK. Prevalence and predictors of posttraumatic stress disorder in adult survivors of childhood cancer, Pediatrics. 2010 May;125(5):e1124-34.
Evans S, Moieni M, Taub R, Subramanian SK, Tsao JC, Sternlieb B, Zeltzer LK. Iyengar yoga for young adults with rheumatoid arthritis: results from a mixed-methods pilot study. J Pain Symptom Manage. 2010 May;39(5):904-13.
Evans S, Taub R, Tsao JC, Meldrum M, Zeltzer LK. Sociodemographic factors in a pediatric chronic pain clinic: The roles of age, sex and minority status in pain and health characteristics. J Pain Manag. 2010 Jul;3(3):273-281.
Casillas J, Kahn KL, Doose M, Landier W, Bhatia S, Hernandez J, Zeltzer LK; in collaboration with Padres Contra El Cáncer. Transitioning childhood cancer survivors to adult-centered healthcare: insights from parents, adolescent, and young adult survivors. Psychooncology. 2010 Sep;19(9):982-90.
Kadan-Lottick NS, Zeltzer LK, Liu Q, Yasui Y, Ellenberg L, Gioia G, Robison LL, Krull KR. Neurocognitive Functioning in Adult Survivors of Childhood Non-Central Nervous System Cancers. J Natl Cancer Inst. 2010 Jun 16;102(12):881-93. Epub 2010 May 10.
Zeltzer LK, Jensen MP. An interview with Lonnie Zeltzer. Contemporary Hypnosis, 2010: 27(4): 291-302.
Buchbinder D, Casillas J, Zeltzer L. Meeting the Psychosocial Needs of Sibling Survivors: A Family Systems Approach. J Pediatr Oncol Nurs. 2011 May-Jun; 28(3):123-36. Epub 2010 Nov 22.PubMed PMID: 21098333.
Evans, S, Meldrum, M, Tsao, JCI, Fraynt, R, & Zeltzer, LK Associations between parent and child pain and functioning in a pediatric chronic pain sample: a mixed methods approach. International Journal on Disability and Human Development, 2010 Nov 1; 9 (1):11-21. NIHMSID: NIHMS 263123. PubMed PMID: 21643522
Byrne, MW, Evan, E, Goshin, LS, Erlich, MD, Kim, J, Saroyan, JM, Zeltzer, LK Parent self-efficacy for managing pain in seriously ill children and adolescents nearing end-of-life. Palliative and Supportive Care 2011: 9, 137-147.
Casillas J, Castellino SM, Hudson MM, Mertens AC, Lima IS, Liu Q, Zeltzer LK, Yasui Y, Robison LL, Oeffinger KC. Impact of insurance type on survivor-focused and general preventive health care utilization in adult survivors of childhood cancer: The Childhood Cancer Survivor Study (CCSS). Cancer. 2011 May 1;117(9):1966-75. doi: 10.1002/cncr.25688. Epub 2010 Nov 10. PubMed PMID: 21509774.
Evans S, Cousins L, Tsao JC, Sternlieb B, Zeltzer LK. Protocol for a randomized controlled study of Iyengar yoga for youth with irritable bowel syndrome. Trials. 2011 Jan 18;12:15. PubMed PMID: 21244698; PubMed Central PMCID:PMC3033835.
Evans S, Cousins L, Tsao JC, Subramanian S, Sternlieb B, Zeltzer LK. A randomized controlled trial examining Iyengar yoga for young adults with rheumatoid arthritis: a study protocol. Trials. 2011 Jan 21;12:19. PubMed PMID: 21255431; PubMed Central PMCID: PMC3033352.
von Baeyer CL, Lin V, Seidman LC, Tsao JC, Zeltzer LK. Pain charts (body maps or manikins) in assessment of location of pediatric pain. Pain Management, 2011 Jan;1(1):61-68. PubMed PMID: 21572558
Kunin-Batson A, Kadan-Lottick N, Zhu L, Cox C, Bordes-Edgar V, Srivastava DK, Zeltzer L, Robison LL, Krull KR. Predictors of independent living status in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2011 Feb 3. doi: 10.1002/pbc.22982. [Epub ahead of print]PubMed PMID: 21294244.
Zebrack BJ, Stuber ML, Meeske KA, Phipps S, Krull KR, Liu Q, Yasui Y, Parry C, Hamilton R, Robison LL, Zeltzer LK. Perceived positive impact of cancer among long-term survivors of childhood cancer: a report from the childhood cancer survivor study. Psychooncology. 2012 Jun; 21 (6): 630-9.doi: 10.1002/pon.1959. Epub 2011 Mar 22. PubMed PMID: 21425388.PubMed Central PMCID: PMC3697081.
Allen LB, Lu Q, Tsao JC, Hayes LP, Zeltzer LK. Depression partially mediates the relationship between alexithymia and somatization in a sample of healthy children. Journal of Health Psychology, 2011. 16, 1177-1186. PMID: 21464112.
Clanton NR, Klosky JL, Li C, Jain N, Srivastava DK, Mulrooney D, Zeltzer L, Stovall M, Robison LL, Krull KR. Fatigue, vitality, sleep, and neurocognitive functioning in adult survivors of childhood Cancer: A report from the childhood cancer survivor study. Cancer. 2011 Apr 11. doi: 10.1002/cncr.25797. [Epub ahead of print] PubMed PMID: 21484777.
Allen LB, Tsao JC, Hayes LP, Zeltzer LK. Peer mentorship to promote effective pain management in adolescents: study protocol for a randomized controlled trial. Trials. 2011 May 22;12:132. PubMed PMID:21600053
Stuber ML, Meeske KA, Leisenring W, Stratton K, Zeltzer LK, Dawson K, Kazak AE, Zebrack B, Mertens AC, Robison LL, Krull KR. Defining medical posttraumatic stress among young adult survivors in the Childhood Cancer Survivor Study. Gen Hosp Psychiatry. 2011 Jul-Aug;33(4):347-53. Epub 2011 May 25.
Binder WS, Zeltzer LZ, Simmons CF, Mirocha J, and Pandya A; The Father in the Hallway: Posttraumatic Stress Reactions in Fathers of NICU Babies. Psychiatric Annals 08/2011; 41(8):396-402.
Lu, Q., Krull, K. R., Leisenring, W., Owen J., Kawashima, T., Tsao, J. C. I., Zebrack B., Mertens, A.C., Armstrong, G. T., Stovall, M., Robison, L.L., & Zeltzer, L. K. Pain in long-term adult survivors of childhood cancers and their siblings: A report from the Childhood Cancer Survivor Study. Pain. 2011 Nov;152(11):2616-24. Epub 2011 Sep 9.PubMed PMID:21907493
Tsao JC, Evans S, Seidman LC, Zeltzer LK. Healthcare utilization for pain in children and adolescents: a prospective study of laboratory and non-laboratory predictors of care-seeking. Int J Adolesc Med Health. 2011;23(3):287-92. PubMed PMID: 22191197; PubMed Central PMCID: PMC3246362.
Buchbinder D, Casillas J, Krull KR, Goodman P, Leisenring W, Recklitis C, Alderfer MA, Robison LL, Armstrong GT, Kunin-Batson A, Stuber M, Zeltzer LK. Psychological outcomes of siblings of cancer survivors: A report from the Childhood Cancer Survivor Study. Psycho-Oncology. 2011 Dec; 20(12):1259-68. doi:10.1002/pon.1848. Epub 2010 Oct 22.
Haas, K., Lu, Q., Evans, S., Tsao, J.C.I., Zeltzer, L.K. The relationship between resting blood pressure and laboratory induced pain among healthy children. Gender Medicine. 2011 Dec; 8(6):388-98. Epub 2011 Oct 28. PubMed PMID: 22035675
Ho P, Tsao JC, Bloch L, Zeltzer LK. The impact of group drumming on social-emotional behavior in low-income children. Evid Based Complement Alternat Med. 2011; 2011:250708. Epub 2011 Feb 13. PubMed PMID: 21660091
Evans, S., Moieni, M., Subramanian, S.K., Tsao, J. C. I., Sternlieb, B., & Zeltzer, L. K. Now I see a brighter day: Expectations and perceived benefits of an Iyengar yoga intervention for young patients with rheumatoid arthritis. Journal of Yoga & Physical Therapy, 2011, 1 (1).
Clemente I, Heritage J, Meldrum ML, Tsao JC, & Zeltzer LK. Preserving the Child as a Respondent: Initiating Patient-Centered Interviews in a U.S Outpatient Tertiary Care Pediatric Pain Clinic. Communication and Medicine. 2012, 9, 203-213
Kahalley LS, Robinson LA, Tyc VL, Hudson MM, Leisenring W, Stratton K, Mertens AC, Zeltzer L, Robison LL, Hinds PS. Risk factors for smoking among adolescent survivors of childhood cancer: A report from the childhood cancer survivor study. Pediatr Blood Cancer. 2012 Mar; 58(3):428-34.
Allen LB, Tsao JCI, Seidman LC, Ehrenreich-May J, Zeltzer LK. A unified, transdiagnostic treatment for adolescents with chronic pain and comorbid anxiety and depression. Cognitive and Behavioral Practice. 2012, Jan; 19 (1): 56-67.
Tsao JCI, Lu Q, & Zeltzer, LK, Beyond traditional cognitive-behavioral therapy: Novel psychological and alternative approaches to pediatric pain. Journal of Pain Management, 2012, 1(2), 81-89.
Buchbinder D, Mertens AC, Zeltzer LK, Leisenring W, Goodman P, Lown EA, Alderfer MA, Recklitis C, Oeffinger K, Armstrong GT, Hudson M, Robison LL, Casillas J. Cancer prevention and screening practices of siblings of childhood cancer survivors: a report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1078-88. doi:10.1158/1055-9965.EPI-11-1095. Epub 2012 May 10. PubMed PMID: 22576363; PubMed Central PMCID: PMC3392493.
Evans S, Moieni M, Sternlieb B, Tsao JC, Zeltzer LK, Yoga for youth in pain: the UCLA pediatric pain program model. Holist Nurs Pract. 2012 Sep; 26(5):262-71. doi: 10.1097/HNP.0b013e318263f2ed. PubMed PMID: 22864296
Tsao JCI, Evans S, Seidman LC, & Zeltzer LK, Experimental pain responses in children with chronic pain and healthy children: How do they differ? Pain Research and Management, 2012, 17: 103-109. PMID: 22518373
Sudan M, Kheifets L, Arah O, Olsen J, Zeltzer L. Prenatal and Postnatal Cell Phone Exposures and Headaches in Children. Open Pediatr Med Journal. 2012 Dec 5; 6(2012): 46-52. PMID: 23750182
Jacob E, Stinson J, Duran J, Gupta A, Gerla M, Ann Lewis M, Zeltzer L. Usability testing of a Smartphone for accessing a web-based e-diary for self-monitoring of pain and symptoms in sickle cell disease. J Pediatr Hematol Oncol. 2012 Jul; 34 (5):326-35. PubMed PMID: 22627570; PubMed Central PMCID:PMC3382023.
Jarrett M, Heitkemper M, Czyzewski D, Zeltzer L, Shulman RJ. Autonomic nervous system function in young children with functional abdominal pain or irritable bowel syndrome. J Pain. 2012 May;13(5):477-84. Epub 2012 Apr 20. PubMed PMID:22520688.
Donovan E, Mehringer S, Zeltzer LK. A qualitative analysis of adolescent, caregiver, and clinician perceptions of the impact of migraines on adolescents' social functioning. Pain Manag Nurs. 2013 Dec;14(4):e135-41. doi:10.1016/j.pmn.2011.09.002. Epub 2011 Nov 4. PubMed PMID: 24315265; PubMed Central, PMCID: PMC3857540.
Brinkman TM, Zhang N, Ullrich NJ, Brouwers P, Green DM, Srivastava DK, Zeltzer LK, Stovall M, Robison LL, Krull KR. Psychoactive medication use and neurocognitive function in adult survivors of childhood cancer: A report from the childhood cancer survivor study. Pediatr Blood Cancer. Pediatr Blood Cancer. 2013 Mar;60(3):486-93.doi: 10.1002/pbc.24255. Epub 2012 Jul 27. PubMed PMID: 22848025; PubMed Central, PMCID: PMC3494805.
Donovan E, Mehringer S, Zeltzer LK. Assessing the feasibility of a Web-based self-management program for adolescents with migraines and their caregivers. Clin Pediatr (Phila). 2013 Jul;52(7):667-70. doi: 10.1177/0009922812447679. Epub 2012 May 21. PubMed PMID: 22615486.
Jacob E, Pavlish C, Duran J, Stinson J, Lewis MA, Zeltzer L. Facilitating pediatric patient-provider communications using wireless technology in children and adolescents with sickle cell disease. J Pediatr Health Care. 2013, Jul-Aug;27(4):284-92. doi: 10.1016/j.pedhc.2012.02.004. Epub 2012 Mar 24. PubMed, PMID: 22446036; PubMed Central PMCID: PMC3449226.
Lown EA, Mertens AC, Korcha RA, Leisenring W, Hudson MM, Greenfield TK, Robison LL, Zeltzer LK. Prevalence and predictors of risky and heavy alcohol consumption among adult siblings of childhood cancer survivors. Psychooncology.2013 May;22(5):1134-43. doi: 10.1002/pon.3121. Epub 2012 Jun 27. PubMed PMID:22736595; PubMed Central PMCID: PMC3648621.
Brinkman TM, Ullrich NJ, Zhang N, Green DM, Zeltzer LK, Lommel KM, Brouwers P, Srivastava DK, Jain N, Robison LL, Krull KR. Prevalence and predictors of prescription psychoactive medication use in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Cancer Surviv. 2013, Mar;7(1):104-14. doi: 10.1007/s11764-012-0250-x. Epub 2012 Dec 8. PubMed PMID:23224753; PubMed Central PMCID: PMC3568188.
Payne LA, Seidman LC, Lung K., Zeltzer LK, & Tsao JCI. Relationship of neuroticism and laboratory pain in healthy children: Does anxiety sensitivity play a role? Pain. 2013 Jan;154(1):103-9. doi: 10.1016/j.pain.2012.09.013. Epub 2012 Sep 29.PMID: 23158759
Jacob E, Duran J, Stinson J, Lewis MA, Zeltzer L. Remote monitoring of pain and symptoms using wireless technology in children and adolescents with sickle cell disease. J Am Assoc Nurse Pract. 2013 Jan;25(1):42-54. doi: 10.1111/j.1745-7599.2012.00754.x. Epub2012Jul 12.PMID:23279278
Evans S, Moieni M, Lung K, Tsao J, Sternlieb B, Taylor M, Zeltzer L. Impact of Iyengar yoga on quality of life in young women with rheumatoid arthritis. Clin J Pain. 2013 Nov;29(11):988-97. doi: 10.1097/AJP.0b013e31827da381. PubMed PMID:23370082; PubMed Central PMCID: PMC3644391.
Tsao JC, Seidman LC, Evans S, Lung KC, Zeltzer LK, Naliboff BD. Conditioned pain modulation in children and adolescents: effects of sex and age. J Pain. 2013, Jun;14(6):558-67. doi: 10.1016/j.jpain.2013.01.010. Epub 2013 Mar 27. PubMed, PMID: 23541066; PubMed Central PMCID: PMC3672325.
Evans S, Seidman LC, Lung KC, Zeltzer LK, Tsao JC. Sex differences in the relationship between maternal fear of pain and children's conditioned pain modulation. J Pain Res. 2013;6:231-8. doi: 10.2147/JPR.S43172. Epub 2013 Mar 20. PMID:23569396
Lu Q, Zeltzer LK, Tsao JCI. Multiethnic Differences in Responses to Laboratory Pain Stimuli Among Children.ﾠHealth Psychology. 2013 Aug;32(8):905-14.] doi:10.1037/a0032428. Epub 2013 May 13. PubMed PMID: 23668844; PubMed Central PMCID: PMC3742024.
Evans S, Seidman LC, Tsao JCI, Lung KC, Zeltzer LK, & Naliboff, BD. Heart rate variability as a biomarker for autonomic nervous system response differences between children with chronic pain and healthy control children. J of Pain Research. 2013 Jun 12:6 449-457; doi: 10.2147/JPR.S43849. Print 2013. PubMed PMID: 23788839; PubMed Central PMCID: PMC3684221.
Yazdani S, Zeltzer L. Treatment of chronic pain in children and adolescents. Pain Manag. 2013 Jul;3(4):303-14. doi: 10.2217/pmt.13.25. PubMed PMID: 24654816.
Brinkman TM, Zhu L, Zeltzer LK, Recklitis CJ, Kimberg C, Zhang N, Muriel AC, Stovall M, Srivastava DK, Robison LL, Krull KR. Longitudinal patterns of psychological distress in adult survivors of childhood cancer. Br J Cancer. 2013, Sep 3;109(5):1373-81. doi: 10.1038/bjc.2013.428. Epub 2013 Jul 23. PubMed PMID: 23880828; PubMed Central PMCID: PMC3778287.
Schwartz L, Seidman L, Zeltzer LK, & Tsao JCI. Mother-child concordance for pain location in a pediatric chronic pain sample. J Pain Manage. 2013;6(2):135-145
Goldenberg D, Payne LA, Hayes LP, Zeltzer LK, & Tsao JCI. Peer mentorship teaches social tools for pain self-management: A case study. Journal of Pain Management. 2013, 6, 61-68
Evans S, Sternlieb B, Zeltzer LK, & Tsao JCI. Iyengar yoga and the use of props for pediatric chronic pain: A case study. Alternative Therapies in Health and Medicine. 2013 Sep-Oct; 19(5):66-70. PMID: 23981408
Mertens AC, Brand S, Ness KK, Li Z, Mitby PA, Riley A, Patenaude AF, Zeltzer L. Health and Well-Being in Adolescent Survivors of Early Childhood Cancer: A Report from the Childhood Cancer Survivor Study. Psycho-Oncology. 2014 Mar;23(3):266-75. Doi:10.1002/pon.3414. Epub 2013 Oct 4.
Brinkman TM, Zhang N, Recklitis CJ, Kimberg C, Zeltzer LK, Muriel AC, Stovall M, Srivastava DK, Sklar CA, Robison LL, Krull KR. Suicide ideation and associated mortality in adult survivors of childhood cancer. Cancer. 2014 Jan 15; 120(2):271-7. Epub 2013 Oct 7. PMID: 24122148
Babikian T, Zeltzer L, Tachdjian V, Henry L, Javanfard E, Tucci L, Goodarzi M, Tachdjian R. Music as Medicine: A Review and Historical Perspective. Alternative and Complimentary Therapies. 2013 October; 19 (5) 251-54.
Tsao JC, Jacob E, Seidman LC, Lewis MA, Zeltzer LK. Psychological aspects and hospitalization for pain crises in youth with sickle-cell disease. J Health Psychol. 2014 Mar;19(3):407-16. doi: 10.1177/1359105312471570. Epub 2013 Feb 13. PubMed PMID: 23407129; PubMed Central PMCID: PMC3744610.
Tsao JC, Li N, Parker D, Seidman LC, Zeltzer LK. Pubertal status moderates the association between mother and child laboratory pain tolerance. Pain Res Manag. 2014 Jan-Feb;19(1):23-9. Epub 2013 Dec 23.
Chou R, Cruciani RA, Fiellin DA, Compton P, Farrar JT, Haigney MC, Inturrisi C, Knight JR, Otis-Green S, Marcus SM, Mehta D, Meyer MC, Portenoy R, Savage S, Strain E, Walsh S, Zeltzer L. Methadone safety: a clinical practice guideline from the American Pain Society and College on Problems of Drug Dependence, in collaboration with the Heart Rhythm Society. J Pain. 2014 Apr;15(4):321-37. doi: 10.1016/j.jpain.2014.01.494.
Evans S, Lung KC, Seidman LC, Sternlieb B, Zeltzer LK, Tsao JC. Iyengar yoga for adolescents and young adults with irritable bowel syndrome. J Pediatr Gastroenterol Nutr. 2014 Aug;59(2):244-53.
Ford JS, Kawashima T, Whitton J, Leisenring W, Laverdière C, Stovall M, Zeltzer LK, Robison LL, Sklar CA. Psychosexual Functioning Among Adult Female Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study. Journal of Clinical Oncolgy.2014 Oct 1;32(28):3126-36
Payne LA, Hibel LC, Granger DA, Tsao JC, Zeltzer LK. Relationship of Salivary Alpha Amylase and Cortisol to Social Anxiety in Healthy Children Undergoing Laboratory Pain Tasks. J Child Adolesc Behav. 2014;2. pii: 1000129.
Jacob E, Chan VW, Hodge C, Zeltzer L, Zurakowski D, Sethna NF. Sensory and Thermal Quantitative Testing in Children with Sickle Cell Disease. J Pediatr Hematol Oncol. 2015 April; 37(3): 185-89.
Prasad P, Hardy K, Zhang N, Edelstein K, Srivastava D, Zeltzer LK, Stovall M, Seibel N, Leisenring W, Armstrong G, Robison L, Krull K. Psychosocial and Neurocognitive Outcomes in Adult Survivors of Adolescent and Early Young Adult Cancer: A Report from the Childhood Cancer Survivor Study. J Clin Oncol. 2015 Aug 10;33(23):2545-52.
Asarnow J, Rozenman M, Wiblin J, Zeltzer L. Integrated Medical-Behavioral Care Compared With Usual Primary Care for Child and Adolescent Behavioral Health: A Meta-analysis. JAMA Pediatr. 2015 Oct;169(10):929-37.
Buchbinder D, Oeffinger K, Franco-Villalobos C, Yasui Y, Alderfer MA,Armstrong GT, Casillas J, Ford J, Krull KR, Leisenring W, Recklitis C, Robison LL, Zeltzer LK, Lown EA. Tobacco use among siblings of childhood cancer survivors: A report from the childhood cancer survivor study. Pediatr Blood Cancer. 2016 Feb;63(2):326-33
Payne LA, Rapkin AJ, Lung KC, Seidman LC, Zeltzer LK, Tsao JC. Pain Catastrophizing Predicts Menstrual Pain Ratings in Adolescent Girls with Chronic Pain. Pain Med. 2015 Jul 27. doi: 10.1111/pme.12869. [Epub ahead of print]
Teen Pain Help Foundation is designed to help children and teenagers with chronic pain by raising funds for treatment, research, education, and increased public awareness. Together we can help children and families going through chronic pain conquer it, and live the happy, healthy lives they deserve. Visit the website here.
The American Pain Society is a multidisciplinary community that brings together a diverse group of scientists, clinicians and other professionals to increase the knowledge of pain and transform public policy and clinical practice to reduce pain-related suffering. APS envisions a world where pain prevention and relief are available to all people. Visit the website here.
CMF is a 501(c)(3) non-profit organization whose mission is to provide musical instruments and music therapy to children, adolescents, and young adults with chronic conditions and life-altering illnesses, and to support research on the effects of music therapy. Visit the website here.
Dr. Elliot Krane talks about chronic pain. He gives insight into why chronic pain occurs in some people and not others and draws apt metaphors for what the children/teens are experiencing.
See the video here.
PARTH R BHATT